<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN"> <html lang="ja"> <head> <meta http-equiv="content-type" content="text/html;charset=UTF-8"> <title>xvzmi>~</title> <link href="css/achievement.css" rel="stylesheet" type="text/css"> </head> <body> <div id="container"> <div id="title_bar"> <td>xvzmi>~ Achievement</td> </div><!--title_bar--> <div id="main_area"> <h3 class="year">%2018s^b30t^ </h3> <h4 class="gyouseki">f[S֊e0Wf Publication & Book</h4> <ol> <li> <span class="researcher">Hein ML, Matsushita H, Morino M, Koga Y, Michiue H, Nishiki T, Tomizawa K, Matsui H.</span><br> <span class="reserch">Oxytocin inhibits corticosterone-induced apoptosis in primary hippocampal neurons.</span><br> <span class="publish">Neuroscience</span> 379:383-389, 2018. May<br><br> </li> <li> <span class="researcher">(g yN.</span><br> <span class="reserch">^yL}OTir>eQ.</span><br> <span class="publish"><a href="https://www.kagakudojin.co.jp/book/b352192.html" target="_blank">03^yL}Sf[ 3o0D0~0Sf[n0Ig0i0S0~0g000K00</a></span> hlu0>\tff_ }, Sf[ TN.<br> ISBN: 9784759817263<br> 2018 Mar <br><br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">A scientific journey from the protein theraphy to BNCTyr%Ro </span><br> <span class="researcher">Matsui Hideki</span><br> <span class="place">,{95Ve,gutf[O'YO<br> 00000000ؚ~g0K0L00VOp4Xؚ~g^ </span><br> <span class="date">3g28^3g30e</span><br> <br> </li> <li> <span class="reserch">Lineage-restricted dedifferentiation of neurons by transient expression of YAP-TAZ O;u000000 0^yL}y^0}ހn0SQX'`h0pu8^ 0 </span><br> <span class="researcher">Fujimura Atsushi</span><br> <span class="place">,{95Ve,gutf[O'YO<br> 00000000ؚ~g0K0L00VOp4Xؚ~g^ </span><br> <span class="date">3g28^3g30e</span><br> <br> </li> <li> <span class="reserch"> The function of brain turmo stem cellO;u000000 0^yL}y^0}ހn0SQX'`h0pu8^ 0 </span><br> <span class="researcher">Michiue Hiroyuki, Fujimura Atsushi, Matsushita Hiroyuki, Nishiki Tei-ichi, Matsui Hideki</span><br> <span class="place">,{95Ve,gutf[O'YO<br> 00000000ؚ~g0K0L00VOp4Xؚ~g^ </span><br> <span class="date">3g28^3g30e</span><br> <br> </li> <li> <span class="reserch">Expression and Localization of Doc2B in podocytes in rat kidney glomeruli.0000 </span><br> <span class="researcher">Yamada Yuya, Iwafuji Ryouta, Matsushita Hiroyuki, Michiue Hiroyuki, Fujimura Atsushi, Matsui Hideki, Nishiki Tei-ichi</span><br> <span class="place">,{95Ve,gutf[O'YO<br> 00000000ؚ~g0K0L00VOp4Xؚ~g^ </span><br> <span class="date">3g28^3g30e</span><br> <br> </li> </ol> <br><br> <br><hr><br> <h3 class="year">%2017s^b29t^ </h3> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">Oxytocin prevents corticosterone-induced dendritic atrophy in the primary mouse hippocampal neurons. (poster)</span><br> <span class="researcher">Sato A, Hein ML, Matsushita H, Michiue, H, Nishiki T, Matsui H.</span><br> <span class="place">,{94V e,gutf[O'YO<br> 0000000\m~g\m~g^ </span><br> <span class="date">3g28e03g30e</span><br> <br> </li> <li> <span class="reserch">The novel drug screening method with drug repositioning against actin polymerization. (poster)</span><br> <span class="researcher">Michiue H, Hayashi K, Matsushita H, Nishiki T, Matsui H.</span><br> <span class="place">,{94V e,gutf[O'YO<br> 0000000\m~g\m~g^ </span><br> <span class="date">3g28e03g30e</span><br> <br> </li> <li> <span class="reserch">Oxytocin prevents corticosterone-induced dendritic atrophy in mouse hippocampal neurons.S- </span><br> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">hYRތ0Sތ</font><br> <span class="researcher">Hein Min Latt0PO䅜N}0SՈh0~g NZS-f0S N[KN0Qg{S0(gyN0~gNy9j</span><br> <span class="place">,{69Ve,gutf[O-NVVV0WeO<br> _q\'Yf[ub eN00000000_\^ </span><br> <span class="date">10g28^10g28e</span><br> <br> </li> </ol> <h3 class="year">%2016s^b28t^ </h3> <h4 class="gyouseki">f[S֊e0Wf Publication & Book</h4> <ol> <li> <span class="researcher">Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei FY, Fujimura A, Tazawa H, Asai A, Ogo N, Miyachi H, Nishiki T, Tomizawa K, Takei K, Matsui H.</span><br> <span class="reserch">Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization.</span><br> <span class="publish">Sci Rep.6:23372, </span> 2016 Mar <br><br> </li> <li> <span class="researcher">Kondo N, Michiue H, Sakurai Y, Tanaka H, Nakagawa Y, Watanabe T, Narabayashi M, Kinashi Y, Suzuki M, Masunaga S, Ono K.</span><br> <span class="reserch">Detection of H2AX foci in mouse normal brain and brain tumor after boron neutron capture therapy.</span><br> <span class="publish">Rep Pract Oncol Radiother.21(2):108-112, </span> 2016 Mar <br><br> </li> <li> <span class="researcher">(g yN.</span><br> <span class="reserch"><a href="https://bsd.neuroinf.jp/wiki/%E3%82%B7%E3%83%B3%E3%82%BF%E3%82%AD%E3%82%B7%E3%83%B3" target="_blank">000000.</a></span><br> <span class="publish"><a href="https://bsd.neuroinf.jp/wiki/%E3%83%A1%E3%82%A4%E3%83%B3%E3%83%9A%E3%83%BC%E3%82%B8" target="_blank">03yf[xQ0</a> g ^} }, e,g^yL}yf[f[O.</span><br> <span class="publish"> DOI: 10.14931/bsd.6583</span>b<br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">e00 }dRzvk000eW0D0BNCTL00lBv(0000)</span><br> <span class="researcher">S N[KN0~gNy9j</span><br> <span class="place">-N.Ye,g0000000000002016<br> 'Y*#umiuR ( ('Y*^)</span><br> <span class="date">2g16e</span><br> <br> </li> <li> <span class="reserch">The new topical drug delivery system with Cell-Penetrating Peptide (CPP) (0000)</span><br> <span class="researcher">Hiroyuki Michiue0 Mizuki Kitamatsu0Hiroaki Matsushita0Tei-ichi Nishiki0Hideki Matsui</span><br> <span class="place">,{93Ve,gutf[O'YO<br> -gL^00000000000(-gL^^)</span><br> <span class="date">3g22^3g23e</span><br> <br> </li> <li> <span class="reserch">An innovative approach to solve the BNCT drug problem (S-)</span><br> <span class="researcher">~gNy9j</span><br> <span class="place">1st NRW-Fukushima Joint Symposium on Advances in Medicine <br>"Japanese and German Cutting Edge Technologies for Patient Care"<br> Deichmann Auditorium University Hospital Essen (Germany0Essen)</span><br> <span class="date">9g1^9g2e</span><br> <br> </li> <li> <span class="reserch">e0000000l0(uD0f0bF0d0k0`'`3k vx0n0lBvRg0zv (S-)</span><br> <span class="researcher">S N[KN</span><br> <span class="place">00000000002016<br> 0000000 (,p8bQ^)</span><br> <span class="date">9g21^9g22e</span><br> <br> </li> <li> <span class="reserch">Fluvoxamine (SSRI), inhibits glioblastoma invasion by inhibition of actin polymerization (S-)</span><br> <span class="researcher">H.Michiue0K.Hayashi0H.Matsushita0T.Nishiki0H.Matsui</span><br> <span class="place">European Association of Neuro-Oncology(EANO) 2016 meeting<br> Congress Center Rosengarten (Mannheim)</span><br> <span class="date">10g12^10g16e</span><br> <br> </li> <li> <span class="reserch">Neuroprotective effect of oxytocin on corticosterone-induced apoptosis in mouse hippocampal neurons (S-)</span><br> <span class="researcher">Hein Min Latt0Miku Morino0Yuuri Koga0Hiroaki Matsushita0Hiroyuki Michiue0Teiichi Nishiki0Hideki Matsui</span><br> <span class="place">,{68Ve,gutf[O-NVVV0WeO<br> \q\'Yf[ Junko Fukutake Hall</span><br> <span class="date">11g5^11g6e</span><br> <br> </li> <li> <span class="reserch">bF0d000000000(uD0_0`'`00000lBvln0zv (S-)</span><br> <span class="researcher">S N[KN0gsONΐ0ҞOOTf_0^]zf}0~g NZS-f0(gyN0~gNy9j</span><br> <span class="place">,{34Ve,g3k vf[O<br> 2u^[XK\000(2u^^)</span><br> <span class="date">12g4^12g6e</span><br> <br> </li> </ol> <h4 class="gyouseki">b_o Invited Lectures</h4> <ol> <li> <span class="reserch">BNCTn0_00n0e00 }STirzv (S-)</span><br> <span class="researcher">S N[KN</span><br> <span class="place">,{51VxQWCQ }Sf[0000<br> enW ( Pwe^)</span><br> <span class="date">8g25^8g27e</span><br> <br> </li> <li> <span class="reserch">bF0d0I{n0BBBNSTir0(uD0_0 e`'`3k vlBvn0zv (S-)</span><br> <span class="researcher">S N[KN</span><br> <span class="place">DSANJDrug Seeds Alliance Network Japan u`%RFUNJO2016t^^Yg<br> 'Y*#umiuR ( ('Y*^)</span><br> <span class="date">9g1^9g2e</span><br> <br> </li> <li> <span class="reserch">BNCTn0_00n0e00 }STirzv 0N'`00 }00000 0 (S-)</span><br> <span class="researcher">S N[KN</span><br> <span class="place">'Y*;Sy'Yf[D^\ubL000000HQz;SBv萀000000<br> 'Y*;Sy'Yf[ (ؚi^)</span><br> <span class="date">11g20^11g25e</span><br> <br> </li> </ol> <br><br> <br><hr><br> <h3 class="year">%2015s^b27t^ </h3> <h4 class="gyouseki">f[S֊e Publications</h4> <ol> <li> <span class="researcher">Yamada H, Kikuchi T, Masumoto T, Wei FY, Abe T, Takeda T, Nishiki T, Tomizawa K, Watanabe M, Matsui H, Takei K.</span><br> <span class="reserch">Possible role of cortactin phosphorylation by protein kinase C in actin-bundle formation at growth cone.</span><br> <span class="publish">Biol Cell.[doi: 10.1111/boc.201500032.] </span> 2015 Jun <br><br> </li> <li> <span class="researcher">Wei FY, Zhou B, Suzuki T, Miyata K, Ujihara Y, Horiguchi H, Takahashi N, Xie P, Michiue H, Fujimura A, Kaitsuka T, Matsui H, Koga Y, Mohri S, Suzuki T, Oike Y, Tomizawa K.</span><br> <span class="reserch">Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans.</span><br> <span class="publish">Cell Metab. 21(3):428-442 [doi: 10.1016/j.cmet.2015.01.019]</span> 2015 May <br><br> </li> <li> <span class="researcher">Iguchi Y, Michiue H, Kitamatsu M, Hayashi Y, Takenaka F, Nishiki T, Matsui H.</span><br> <span class="reserch">Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model.</span><br> <span class="publish">Biomaterials.56 10-17 [doi:10.1016/j]</span> 2015 Jul <br><br> </li> <li> <span class="researcher">Nishiki T, Kuroki K, Masumoto T, Matsui H. </span><br> <span class="reserch">Ca<sup/>2+</sup> sensors: synaptotagmins.</span><br> In <i>Presynaptic Terminals,</i>edited by Sumiko M,<br> <span class="publish">Springer Japan, 167-194.</span> <br><br> </li> <li> <span class="researcher">Onishi M, Ichikawa T, Kurozumi K, Inoue S, Maruo T, Otani Y, Fujii K, Ishida J, Shimazu Y, Yoshida K, Michiue H, Antonio Chiocca E, Date I.</span><br> <span class="reserch">Annexin A2 regulates angiogenesis and invasion phenotypes of malignant glioma.</span><br> <span class="publish">Brain Tumor Pathol.</span> 2015 Feb <br><br> </li> <li> <span class="researcher">Hakata Y, Tsuchiya S, Michiue H, Ohtsuki T, Matsui H, Miyazawa M, Kitamatsu M.</span><br> <span class="reserch">A novel leucine zipper motif-based hybrid peptide delivers a functional peptide cargo inside cells.</span><br> <span class="publish">Chem Commun (Camb). 51(2):413-416 [doi: 10.1039/c4cc07459a.] </span> 2015 Jan<br><br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">00 }0000k000!kNNL00|P[}lBvBNCTn0c2So </span><br> <span class="researcher">~gN y9j</span><br> <span class="place">,{53Ve,gLvlBvf[Of[SƖO<br> 00000000000N</span><br> <span class="date">10g29^10g31e</span><br> <br> </li> <li> <span class="reserch">NOx }[[S00000(uD0_03k vlBv0000n0zvSo </span><br> <span class="researcher">q\S ZS0S N [KN0S~g ^tu0~g N ZS-f0(g yN0~gN y9j</span><br> <span class="place">,{67Ve,gutf[O-NVVV0WeO<br> s|P[000000000000\000</span><br> <span class="date">10g24^10g25e</span><br> <br> </li> <li> <span class="reserch">Peptide Zippering0NW0_0e00000}ހQ\eQln0iSo </span><br> <span class="researcher">onEm SUu0S N [KN0S~g ^tu0~g N ZS-f0(g yN0~gN y9j</span><br> <span class="place">,{67Ve,gutf[O-NVVV0WeO<br> s|P[000000000000\000</span><br> <span class="date">10g24^10g25e</span><br> <br> </li> <li> <span class="reserch">^yL}OTir>eQn0Ca<sup>2+</sup>0000Doc2n0^yL}|k0J0Q00@\(W㉐gSo </span><br> <span class="researcher">\ N*Y0Α RHYP[0(g yN0~g N ZS-f0S N [KN0ؚKj ck0~gN y9j</span><br> <span class="place">,{67Ve,gutf[O-NVVV0WeO<br> s|P[000000000000\000</span><br> <span class="date">10g24^10g25e</span><br> <br> </li> <li> <span class="place"><b>,{14Ve,g000000lxvzOf[SƖO</b></span><br> <span class="researcher">Yeo ^w 0~gN0y9j</span><br> <span class="place">000000\q\</span><br> <span class="date">10g11e</span></li> <br> <li> <span class="reserch">The Development of BSH Fused Cell-penetrating Peptide towards Clinical Applicationposter </span><br> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">Excellent Poster Award</font> <br> <span class="researcher">Hiroyuki Michiue, Yoshiya Iguchi, Mizuki Kitamatsu, Hiroaki Matsushita, Teiichi Nishiki,Hideki Matsui</span><br> <span class="place">ICRR2015 -15th International Congress of Radiation Research-<br> Kyoto International Conference Center</span><br> <span class="date">25-29 May</span><br> <br> </li> <li> <span class="reserch">`'`Ҟrkk0[Y00bk vp53 Fragment Peptiden00000000h0L}vv\eQk000lBvRgn0i0000 </span><br> <span class="researcher">o0u aPy0S N [KN0S~g ^tu0~g N ZS-f0(g yN0~gN y9j</span><br> <span class="place">,{92Ve,gutf[O'YO<br> ^y8bVU\:y4X</span><br> <span class="date">3g21^3g23e</span><br> <br> </li> <li> <span class="reserch">e0000v\eQl0(uD0_0000000b6R}v0000n0zv0000 </span><br> <span class="researcher">S N [KN0'YENO HY0P[0S~g ^tu0~g N ZS-f0(g yN0~gN y9j</span><br> <span class="place">,{92Ve,gutf[O'YO<br> ^y8bVU\:y4X</span><br> <span class="date">3g21^3g23e</span><br> <br> </li> <li> <span class="reserch">3k vy^0}ހk000@{Qv0}ހx0n0RSh0b@{eun0UO0000 </span><br> <span class="researcher">-Nq\ 'Y0S N [KN0g BhNΐ0~g N ZS-f0(g yN0~gN y9j</span><br> <span class="place">,{92Ve,gutf[O'YO<br> ^y8bVU\:y4X</span><br> <span class="date">3g21^3g23e</span><br> <br> </li> <li> <span class="reserch">F0d0uh0 N[[n0lBvjvh0W0f0n0000000So </span><br> <span class="researcher">~gNy9j0~g NZS-f</span><br> <span class="place">,{92Ve,gutf[O'YO<br> ^y8bVOp4X 000000000</span><br> <span class="date">3g21^3g23e</span><br> <br> </li> <li> <span class="place"><b>International Symposium on Bio-imaging and Gene Targeting Sciences in Okayama<br> \q\RP[000000ؚ^\NPgbNmi-}bV000000</b></span><br> <span class="researcher">Special Lecture1 ^w 0~gN0y9j</span><br> <span class="place">\q\'Yf[uRz50hTt^_O(</span><br> <span class="date">2g28e-3g1e</span></br></br> </li> </ol> <h4 class="gyouseki">yr%Ro Invited Lecture</h4> <ol> <li> <span class="reserch"> 0ART00000k000Physician Scientistn0b 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place">,{8V0aZ'Yf[HQz;Sf[0000000000^0000000000F0^<br> 00000000Pln08NNl^ </span><br> <span class="date">2g28e-3g1e</span></br></br> </li> </ol> <h4 class="gyouseki">Wf Book</h4> <ol> <li> <span class="reserch">0>e\Sf[n0NxQ0</span><br> <span class="researcher">S N0[KN0~gN0y9j</span><br> <span class="publish">h!-11000 }-N'`P[UcIcϑlBNCT p310-311</span><br> <span class="date">g Pf^ 2015t^9g20ezvX</span></br></br> </li> </ol> <br><br> <br><hr><br> <h3 class="year">%2014s^b26t^ </h3> <h4 class="gyouseki">f[S֊e Publications</h4> <ol> <li> <span class="researcher">S N[KN0'YENOHY0P[0~gNy9j </span><br> <span class="reserch">0000k000L}v\eQl0(uD0_0ؚxm}vdRn0zv</span><br> <span class="publish">x}|lp (FRAGRANCE JOURNAL) [No.413]</span> 2014.11.15zvX<br><br> </li> <li> <span class="researcher">Ichikawa T, Kurozumi K, Michiue H, Ishida J, Maeda Y, Kondo E, Kawasaki A, Date I.</span><br> <span class="reserch">Reduced neurotoxicity with combined treatment of high-dose methotrexate, cyclophosphamide, doxorubicin, vincristine and prednisolone (M-CHOP) and deferred radiotherapy for primary central nervous system lymphoma.</span><br> <span class="publish">Clin Neurol Neurosurg. 127:106-111.</span> 2014 Nov<br><br> </li> <li> <span class="researcher">Ohmori I, Kawakami N, Liu S, Wang H, Miyazaki I, Asanuma M, Michiue H, Matsui H, Mashimo T, Ouchida M. </span><br> <span class="reserch">Methylphenidate improves learning impairments and hyperthermia-induced seizures caused by an Scn1a mutation.</span><br> <span class="publish">Epilepsia. [doi:10.1111/epi.12750.] </span> 2014 Aug<br><br> </li> <li> <span class="researcher">Ookubo N, Michiue H, Kitamatsu M, Kamamura M, Nishiki T, Ohmori I, Matsui H. </span><br> <span class="reserch">The transdermal inhibition of melanogenesis by a cell-membrane-permeable peptide delivery system based on poly-arginine.</span><br> <span class="publish">Biomaterials. 35(15):4508-16.</span> 2014 May<br><br> </li> <li> <span class="researcher">Michiue H, Sakurai Y, Kondo N, Kitamatsu M, Feng B, Nakajima K, Hirota Y, Kawabata S, Nishiki T, <br> Ohmori I,Tomizawa K, Miyatake S, Ono K, Matsui H </span><br> <span class="reserch">The acceleration of boron neutron capture therapy using multi-linked mercaptoundecahydrododecaborate (BSH) fused cell-penetrating peptide.</span><br> <span class="publish">Biomaterials. 35(10):3396-405.</span> 2014 Mar<br><br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">3@mNSj00000͑Tb6Rk000kk0[Y00bxmdoRgn0i0000 </span><br> <span class="researcher">S N[KN0g BhNΐ0q\0uimS0-Nq\'Y0ҞOOTf_0^]zf}0~g NZS-f0(gyN0zE\][N0[oNN0~gNy9j</span><br> <span class="place">,{32Ve,g3k vf[Of[SƖO<br> 0000000000000000000000fm[^ </span><br> <span class="date">11g30^12g2e</span><br> <br> </li> <li> <span class="reserch">3k vy^0}ހk000@{Qv0}ހx0n0RSh0b@{eun0UOSo </span><br> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">hYRތ0Sތ</font><br> <span class="researcher">-Nq\ 'Y0S N[KN0g BhNΐ0~g NZS-f0(gyN0~gNy9j</span><br> <span class="place">,{66Ve,gutf[O-NVV0WeO<br> `1XONAm( e-h0t0B00K0L0000000ؚ~g </span><br> <span class="date">11g1^2e</span><br> <br> </li> <li> <span class="reserch">00000000k000wm^yL}0}ހuX[}cn0RP[_jin0fSo </span><br> <span class="researcher">hΑ *geg0S N[KN0~g NZS-f0q\,g}Nΐ0(gyN0~gNy9j</span><br> <span class="place">,{66Ve,gutf[O-NVV0WeO<br> `1XONAm( e-h0t0B00K0L0000000ؚ~g </span><br> <span class="date">11g1^2e</span><br> <br> </li> <li> <span class="reserch">`'`Ҟrkk0[Y00bk vp53 Fragment Peptide 0000000h0L}vv\eQk000lBvRgn0iSo </span><br> <span class="researcher">o0u aPy0S N[KN0S~g^tu0~g NZS-f0(gyN0~gNy9j</span><br> <span class="place">,{66Ve,gutf[O-NVV0WeO<br> `1XONAm( e-h0t0B00K0L0000000ؚ~g </span><br> <span class="date">11g1^2e</span><br> <br> </li> <li> <span class="reserch">P53bk v00000(uD0_0vL00k0[Y00elBvlzvSo </span> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">*Qyoތ0Sތ</font><br> <span class="researcher">o0u aPy0S N[KN0~gNy9j</span><br> <span class="place">,{46VKb0000Yn0R7_O<br> N^zR\t^wm m0000000000)</span><br> <span class="date">8g3^5e</span><br> <br> <li> <span class="reserch">00000000L0000N(W'`TJ00k0TSOb_bk0S|0Y0q_0000 </span><br> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">*Qy0000ތ0Sތ</font><br> <span class="researcher">Ҟ(g eP*Yΐ0X,g t^7u0'Y[ OT~0S N [KN0(g yN0~gN y9j</span><br> <span class="place">,{91Ve,gutf[O'YO<br> PQ\'Yf[ CQ00000</span><br> <span class="date">3g16^3g18e</span><br> <br> </li> <li> <span class="reserch">Cacna1azOP[ Ypu000k0J0Q00P[f0 NhQn0uKaWv</span><br> <span class="researcher">] N g0'Y[ OT~0\g VsO0S N [KN0(g yN0~gN y9j</span><br> <span class="place">,{91Ve,gutf[O'YO<br> PQ\'Yf[ CQ00000</span><br> <span class="date">3g16^3g18e</span><br> <br> </li> <li> <span class="reserch">Cacna1a Ypu000k0J0Q00zvT[iLRn0uKaf</span><br> <span class="researcher">\g VsO0S] ĖNΐ0'Y[ OT~0S N [KN0(g yN0~gN y9j</span><br> <span class="place">,{91Ve,gutf[O'YO<br> PQ\'Yf[ CQ00000</span><br> <span class="date">3g16^3g18e</span><br> <br> </li> </ol> <h4 class="gyouseki">yr%Ro Invited Lecture</h4> <ol> <li> <span class="reserch"> 0`'`3k vk0[Y0000 }-N'`P[܈Bvl (BNCT:Boron Neutron Capture Therapy)</br>WyxvzK00聊^xvz0]0W0f0Wyxvzx0 0</span><br> <span class="researcher">S N0[KN</span><br> <span class="place">,{10V聊^xvz000000000<br> VVL000000~gq\^ </span><br> <span class="date">7g31e</span></br></br> </li> <li> <span class="reserch"> 0e,gn0!kNN;Sf[0bF0NPgb 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place">\q\ wꁻlSOubTSpO}O<br> \q\000000</span><br> <span class="date">5g31e</span> </li> </ol> <br><br> <br><hr><br> <h3 class="year">%2013s^b25t^ </h3> <h4 class="gyouseki">f[S֊e Publications</h4> <ol> <li> <span class="researcher">Fujimura A, Michiue H, Cheng Y, Uneda A, Tani Y, Nishiki T, Ichikawa T, Wei FY, Tomizawa K, Matsui H.</span><br> <span class="reserch">Cyclin g2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics.</span><br> <span class="publish">Neoplasia. 15(11):1272-81. </span>2013 Nov<br><br> </li> <li> <span class="researcher">Yamada H, Abe T, Satoh A, Okazaki N, Tago S, Kobayashi K, Yoshida Y, Oda Y, Watanabe M, Tomizawa K, Matsui H, Takei K.</span><br> <span class="reserch">Stabilization of actin bundles by a dynamin 1/cortactin ring complex is necessary for growth cone filopodia.</span><br> <span class="publish">J Neurosci. 33(10):4514-26. </span>2013 Mar 6<br><br> </li> <li> <span class="researcher">Ohmori I, Hayashi K, Wang H, Ouchida M, Fujita N, Inoue T, Michiue H, Nishiki T, Matsui H.</span><br> <span class="reserch">Inhalation of 10% carbon dioxide rapidly terminates Scn1a mutation-related hyperthermia-induced seizures.</span><br> <span class="publish">Epilepsy Res. 105(1-2): 220 224 </span> 2013 Jul <br><br> </li> <li> <span class="researcher">Ohmori I, Ouchida M, Kobayashi K, Jitsumori Y, Mori A, Michiue H, Nishiki T, Ohtsuka Y, Matsui H</span><br> <span class="reserch">CACNA1A variants may modify the epileptic phenotype of Dravet syndrome</span><br> <span class="publish">Neurobiology of Disease. 50: 209 217, </span>2013 Feb <br><br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">eGFP00000(uD0_0`'`3k vk0[Y00elBvln0zvSo </font></span><br> <span class="researcher">d0uW0J000S N[KN0q\SCfck0'Y[ OT~0(gyN0~gNy9j</span><br> <span class="place">,{65V e,gutf[O-NVVV0WeO<br> ]];Sy'Yf[( Pwe^)</span><br> <span class="date">11g2^3e</span><br> <br> </li> <li> <span class="reserch">00000_(uW0_0ev\eQln0zvh0000000b6R}v0000n00000000So </font></span><br> <span class="researcher">'YENOHY0P[0S N[KN0o0uaPy0Qgw^0'Y[ OT~0(gyN0~gNy9j</span><br> <span class="place">,{65V e,gutf[O-NVVV0WeO<br> ]];Sy'Yf[( Pwe^)</span><br> <span class="date">11g2^3e</span><br> <br> </li> <li> <span class="reserch">00000000k000000N(W'`Tn0b6Rh0Ca<sup/>2+</sup>k000dSo </font></span><br> <span class="researcher">Ҟ(geP*Yΐ0X,gt^7u0'Y[ OT~0S N[KN0(gyN0~gNy9j</span><br> <span class="place">,{65V e,gutf[O-NVVV0WeO<br> ]];Sy'Yf[( Pwe^)</span><br> <span class="date">11g2^3e</span><br> <br> </li> <li> <span class="reserch"> Cell-penetrating D-isomer peptides consisting of pas and the p53 c-terminus induce autophagic cell death of glioma-initiating cells (poster)</span><br> <span class="researcher">Ueda Y, Wei F, Hide T, Michiue H, Takayama K, Kaitsuka T, Nakamura H, Makino K, Kuratsu J, Futaki S, Tomizawa K</span><br> <span class="place">Japan Society of Gene Therapy 2013 19th Annual Meeting<br> Okayama Convention Center</span><br> <span class="date">Jul. 4-6</span><br> <br> </li> <li> <span class="reserch">Industion of in vivo synthetic lethal RNAi responses to treat glioblastoma. (poster)</span><br> <span class="researcher">Michiue H, Nishiki T, Ohmori I, Dowdy S, Matsui H</span><br> <span class="place">Japan Society of Gene Therapy 2013 19th Annual Meeting<br> Okayama Convention Center</span><br> <span class="date">Jul. 4-6</span><br> <br> </li> <li> <span class="reserch">EGFP peptides inhibit the gliblastoma cell proliferation by protein transduction therapy. (poster)</span><br> <span class="researcher">Akdada S, Michiue H, Yamaguchi A, Nishiki T, Ohmori I, Matsui H</span><br> <span class="place">Japan Society of Gene Therapy 2013 19th Annual Meeting<br> Okayama Convention Center</span><br> <span class="date">Jul. 4-6</span><br> <br> </li> <li> <span class="reserch">Inhalation of CO<sub>2</sub> shows a potent and fast-acting anticonvulsant effect against Scn1a mutation-related hyperthermia-induced seizures. (poster)</span> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">Gold posterތ0Sތ</font><br> <span class="researcher">Ohmori I, Hayashi K, Wang HJ, Ouchida M, Matsui H</span><br> <span class="place">30th International Epilepsy Congress<br> Palais des congres de Montreal (Canada)</span><br> <span class="date">Jun. 23-27</span><br> <br> </li> <li> <span class="reserch">CACNA1A variants as a potential genetic modifier of Dravet syndrome. (poster)</span><br> <span class="researcher">Ohmori I, Ouchida M, Kobayashi K, Ohtsuka Y, Matsui H</span><br> <span class="place">30th International Epilepsy Congress<br> Palais des congres de Montreal (Canada)</span><br> <span class="date">Jun. 23-27</span><br> <br> </li> <li> <span class="reserch">Development of Tumor Specific Killing eGFP peptide Against malignant brain tumor (poster)</span><br> <span class="researcher">Michiue H, Akdada S, Yamaguchi A, Kitamatsu M, Ohmori I, Nishiki T, Matsui H</span><br> <span class="place">23rd American Peptide Symposium<br> Hilton Waikola Village, Hawai'i</span><br> <span class="date">Jun. 22-27</span><br> <br> </li> <li> <span class="reserch">Ca<sup/>2+</sup>-dependent activation of SNARE-mediated membrane fusion by removing synaptotagmin (poster)</span><br> <span class="researcher">Masumoto T, Tareste D, Omori I, Michiue H, Galli T, Nishiki T, Matsui H</span><br> <span class="place">Neuro2013,{36Ve,g^yL}yf['YO/,{56Ve,g^yL}Sf[O'YO/,{23Ve,g^yL}Vf[O'YO <br> VzNVO( (N^)</span><br> <span class="date">Jun. 20-23</span><br> <br> </li> <li> <span class="reserch">000000o0`Rh0an06R_0LD00|^yu`lBvn0jvg0B00So </font></span><br> <span class="researcher">~gN y9j</span><br> <span class="place">,{90Ve,gutf[O'YO 0000000kh0P[n0vNOo030 Y[Y000 <br> 0000009XqgN_l8b]:S </span><br> <span class="date">3g27^29e</span><br> <br> </li> </ol> <h4 class="gyouseki">yr%Ro Invited Lecture</h4> <ol> <li> <span class="reserch"> 0e,gn0;Sf[0;SBv0bF0!kNNn0NPgb 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place">,{85V \q\^zubxvzO<br> \q\^z^lub</span><br> <span class="date">12g7e</span> </li> <br><br> </ol> <h4 class="gyouseki">yr1 Patent</h4> <ol> <li> <span class="date">yr1QX02007-188586</span><br> <span class="reserch"> 0uirN'`D}birSs0dRn0uirN'`X7_el 0 <br></span><br> <span class="place">2013t^4g22e0yr1S_g[[zlzl[ </span><br><br> </li> </ol> <br><hr><br> <h3 class="year">%2012s^b24t^ </h3> <h4 class="gyouseki">f[S֊e Publications</h4> <ol> <li> <span class="researcher">Candan G, Michiue H, Ishikawa S, Fujimura A, Hayashi K, Uneda A, Mori A, Ohmori I, Nishiki T, Matsui H, Tomizawa K.</span><br> <span class="reserch">Combining Poly-Arginine with the Hydrophobic Counter-anion 4-(1-Pyrenyl)-Butyric Acid for Protein Transduction in Transdermal Delivery</span><br> <span class="publish">Biomaterials. 33(27):6468-75, </span> 2012 Sep<br><br> </li> <li> <span class="researcher">Okimoto N, Bosch OJ, Slattery DA, Pflaum K, Matsushita H, Wei F-Y, Ohmori M, Nishiki T, Ohmori I, Hiramatsu Y, Matsui H, Neumann ID, Tomizawa K.</span><br> <span class="reserch">RGS2 mediates the anxiolytic fffect of oxytocin.</span><br> <span class="publish">Brain Res. 1453:26-33, </span> 2012 May<br><br> </li> <li> <span class="researcher">Hitsuda T, Michiue H, Kitamatsu M, Fujimura A, Wang F, Yamamoto T, Han X-J, Tazawa H, Uneda A, Ohmori I, Nishiki T, Tomizawa T, Matsui H.</span><br> <span class="reserch">A Protein Transduction Method using Oligo-Arginine (3R) For the Delivery of Transcription Factors into Cell Nuclei.</span><br> <span class="publish">Biomaterials. 33:4665-72,</span> 2012 Jun<br><br> </li> <li> <span class="researcher">Matsushita H, Matsuzaki M, Han XJ, Nishiki T, Ohmori I, Michiue H, Matsui H, Tomizawa K.</span><br> <span class="reserch">Antidepressant-like effect of sildenafil through oxytocin-dependent cyclic AMP response element-binding protein phosphorylation.</span><br> <span class="publish">Neuroscience. 200:13-18,</span> 2012 Jan<br><br> </li> <li> <span class="researcher">Masumoto T, Suzuki K, Ohmori I, Michiue H, Tomizawa K, Fujimura A, Nishiki T, Matsui H.</span><br> <span class="reserch">Ca<sup/>2+</sup>-independent syntaxin binding to the C<sub/>2</sub>B effector region of synaptotagmin.</span><br> <span class="publish">Mol Cell Neurosci. 49:1-8,</span> 2012 Jan<br><br> </li> </ol> <h4 class="gyouseki">} Reviews</h4> <ol> <li> <span class="researcher">Xiao-Jian Han and Kazuhito Tomizawa</span><br> <span class="reserch"><font size="-1">Chapter 7 </font> Protein Delivery</span><br> <span class="publish">Primary and Stem Cells : <font size="-1">Gene Transfer Technologies and Applications </font> 119-133,</span> 2012<br><br> </li> <li> <span class="researcher">Mitsuhiro Matsuzaki, Hiroaki Matsushita, Kazuhito Tomizawa, Hideki Matsui</span><br> <span class="reserch">Oxytocin: a thetapeutic target for mental disorders</span><br> <span class="publish">J Physiol Sci . 62: 119-133,</span> 2012 Jul<br><br> </li> </ol> <h4 class="gyouseki">f[Ozvh Scientific Meeting</h4> <ol> <li> <span class="reserch">NOx }\k000kexmdoVP[n0zvh0_j㉐g <br> New finding and functional analysis of Hypoxia-Induced Expression of Human Glioblastma invasion factor(poster)</span><br> <span class="researcher">S N [KN0Qg {S0^Qg zf}0ҞOO Tf_0 OT R0[o NN0~gNy9j</span><br> <span class="place">,{30V e,g3k vf[Of[SƖO<br> 00000000000^\(^\^)</span><br> <span class="date">Nov. 25-27</span><br> <br> </li> <li> <span class="reserch">0000ꌻ0000lh0jvW000000000k000-N'`P[܈BvldRn0zv<br>So </span><br> <span class="researcher">~gNy9j</span><br> <span class="place">,{29V0;S(uؚRP[xvzO^ <br> #umibS}Txvz@b0wmoR_0000(qgN)</span><br> <span class="date">Nov. 20-21</span><br> <br> </li> <li> <span class="reserch">\ހ>eQCa<sup/>2+</sup>000000000000n0-NWSNARETTSOx0n0P}Th0<br> So </span><br> <span class="researcher">X,gt^7u0'Y[ OT~0S N[KN0(gyN0~gNy9j</span><br> <span class="place">,{64V e,gutf[O-NVVV0WeO<br> ؚw^eS000(ؚw^)</span><br> <span class="date">Oct. 27-28</span><br> <br> </li> <li> <span class="reserch">Requirement of Ca<sup/>2+</sup> binding to the C<sub/>2</sub>B for dissociation of synaptotagmin from <i>trans</i>-SNARE complexes (poster) </span><br> <span class="researcher">Masumoto T, Suzuki K, Tareste D, Ohmori I, Michiue H, Galli T, Nishiki N, Matsui H</span><br> <span class="place">Neuroscience 2012 (42<sup/>nd</sup> annual meeting of the Society for Neurosience)<br> Ernest N. Morial Convention Center (New Orleans, LA, USA)</span><br> <span class="date">Oct. 13-17</span><br> <br> </li> <li> <span class="reserch">Ca<sup/>2+</sup>-independent binding of synaptotagmin to syntaxin via its C<sub/>2</sub>B effector region0(poster)</span><br> <span class="researcher">Nishiki T, Masumoto T, Suzuki K, Fujita M, Fujimura A, Michiue H, Ohmori I, Tomizawa K, Matsui H</span><br> <span class="place">Neuroscience 2012 (42<sup/>nd</sup> annual meeting of the Society for Neurosience)<br> Ernest N. Morial Convention Center (New Orleans, LA, USA)</span><br> <span class="date">Oct. 13-17</span><br> <br> </li> <li> <span class="reserch">SCN9AzOP[ Ypu/YWL0000uPn0聊^Wk0S|0Y0q_</span><br> <span class="researcher">'Y[ OT~0Haijiao Wang0'YQ0u [0\g R_0~gN y9j</span><br> <span class="place">,{46V e,gf00K00f[O<br> ^0000000qgN </span><br> <span class="date">Oct. 11-12</span><br> <br> </li> <li> <span class="reserch">Ca<sup/>2+</sup>-induced dissociation of synaptotagmin from <i>trans</i>-SNARE complexes (poster)</span><br> <span class="researcher">Masumoto T Suzuki K, Omori I Michiue H Nishiki T Matsui H</span><br> <span class="place">Neuroscience 2012,{35Ve,g^yL}yf['YO <br> TSK\VOp4X</span><br> <span class="date">Sep. 18-21</span><br> <br> </li> <li> <span class="reserch">ART00000k00000000j0;Sf[xvzb0000</span><br> <span class="researcher">~gN y9j</span><br> <span class="place">,{89Ve,gutf[O'YO YeYTO000000 <br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">ARTf[uh0W0f0n03t^0/c0ԏc0f0</span><br> <span class="researcher">Qg {S</span><br> <span class="place">,{89Ve,gutf[O'YO YeYTO000000 <br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Dissociation of synaptotagmin from trans-SNARE complexes by Ca<sup>2+</sup>-binding to the C<sub>2</sub>B domain (poster)</span><br> <span class="researcher">Masumoto T, Suzuki K, Ohmori I, Michiue H, Nishiki T, Matsui H</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">The screening and funstional analysin of Novel anti-tumor effect GFP-peptide (poster)</span><br> <span class="researcher">Michiue H, Yamaguchi A, Kitamatsu M, Fujimura A, Hayashi K, Uneda A, Nishiki T, Ohmori I, Matsui H </span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Cyclin G2 enhances Hypoxia-inducced cellular migration of human gioblastoma(poster)</span><br> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">00000000Sތ</font><br> <span class="researcher">Fujimura A, Cheng Y, Uneda A, Tani Y, Michiue H, Ohmori I, Nishiki T, Wei F, Tomizawa K, Matsui H</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Cyclin G2 regulates neuronal differentiation(poster)</span> <img src="image/Sތ.jpg" width="25" height="25" style="vertical-align:middle"><font size="-1">00000000Sތ</font><br> <span class="researcher">Cheng Y, Fujimura A, Michiue H, Nishiki T, Ohmori I, Tomizawa K, Matsui H</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Membrane-permeable p53 C-terminal peptides inhibit the growth of human glioma cancer stemcells(poster)</span><br> <span class="researcher">Ueda Y, Wei F, Kaitsuka T, Michiue H, Mathui H, Kuratsu J, Tomizawa K</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Epilepsy-related voltage-gated calcium channel variants Cav2.1 shows a gain-of-function biophysical property(poster)</span><br> <span class="researcher">Ohmori I, Ouchida M, Kobayashi K, Michiue H, Nishiki T, Matsui H</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> <li> <span class="reserch">Oxytocin-mediated antidepressant effects of sildenafil in male mice by hippocampal MARK/CREB signaling pathway (poster)</span><br> <span class="researcher">Matsuzaki M, Matsushita H, Han XJ, Nishiki T, Ohmori I, Michiue H, Tomizawa K, Matsui H</span><br> <span class="place">,{89Ve,gutf[O'YO<br> wΑ w~g,geSO(</span><br> <span class="date">Mar. 29-31</span><br> <br> </li> </ol> <h4 class="gyouseki">yr%Ro Invited Lectures</h4> <ol> <li> <span class="reserch"> 03Q000000k000F0d0urn0nh0F0d0ulBvn0xvz 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place">,{2V ёl'Yf[ P[i00n0S0S0000000000000n03Q\O(u_j^000000<br> ёl'Yf[D^\ub [000ёlN}S( 000021 ёl^ </span><br> <span class="date">3g16e^18e</span> <br><br> </li> <li> <span class="reserch"> 0>yOLRh030-000000h0RP[- 0<br> 03Q00000000000k000 N[`R0F0d0urn06R_ 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place">N'Yf[0 w^xvz@b0qQ T)R(uxvzO000000<br> N'Yf[ w^xvz@b 'YOp[rq\^ </span><br> <span class="date">2g2e^3e</span> <br><br> </li> <li> <span class="reserch"> 0ART00000f[0RS_聊^xO0d0j0P0eg'Yf[bYek000NPgb 0</span><br> <span class="researcher">~gN0y9j</span><br> <span class="place"> tt'Yf[;Sf[&$<br> tt'Yf[;Sf[ l~ wS:u </span><br> <span class="date">1g16e</span> <br><br> </li> </ol> <hr> </div><!--main_area--> <div id="extra_area"> <p 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